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Donation

• We work only with clinics conducting IUI or IVF. It allows us to concentrate on understanding what the clinics need for their quality work, representatives of the clinics, especially the embryologists in their desire to get a positive outcome of the procedures. In one year, our partners, IVF clinics, conduct about 2,000 IUI or IVF procedures with our donor material.

  Our constant striving for quality and continuous improvement of work helps our partners - IVF clinics to have significant results when working with donor material.

  Frozen reproductive biomaterial is used during in-vitro fertilization in the treatment of infertility. Material is stored in a specially equipped room - cryo-storage.

  The bank stores

  • eggs (oocytes);
  • seminal fluid;
  • embryos.

  Who needs cryopreserved cells

  You can use frozen cells not only in donor programs. Any woman or man can give his healthy gametes for preservation and storage when deciding to postpone parenthood until a later date or before treating a serious illness. Customers can be sure that their eggs or sperm will maintain fertility and high quality.

  The AltraVita cryobank has one of the largest Russian cryobanks, which has a license that meets the requirements of legislation and international standards.

  Methods of cryopreservation

  There are two methods of cryopreservation:

  1. Slow dehydration - elimination of fluid from the cell with replacement with a cryoprotective substance.
  2. Vitrification - ultra-fast freezing with the exception of the crystallization stage. This is the most reliable way in which cells can be stored for years (up to 10 or more) and not lose their characteristics after defrosting.

  The main aim of reproductive cryopreservation is to increase the chances of pregnancy if it is not possible to become pregnant in a natural way.

  What cryobank consists of

  • Donor Bank - provides medical services to infertile couples. Also separately for women and men with infertility. Women without a partner.
  • Personal Bank - provides storage of ejaculate and oocytes of people who decide to postpone the birth of children. Storage of customers biomaterial with a high risk of premature loss or decreased fertility.
  • Well-equipped laboratory - provides verification of material intended for storage. Carries out the procedures for freezing and defrosting of gametes or embryos.

  AltraVita cryobank provides transportation services for reproductive material samples to other reproduction centers.

  Storage conditions

  Cryostorage is a separate room with high-tech equipment that controls environmental parameters. Climatic equipment maintains constant physical conditions. Signal sensors control humidity, temperature, air pressure.

  For storage of biopsy, special tubes, containers, test tubes are provided. Separate storage allows to defrost only one container to use a certain amount of material. All containers are labeled and placed in liquid nitrogen to maintain at constant temperature.

  Medical staff is not permanently staying in the cryostorage. They go in there only in special suits. The signal system of sensors is displayed in the office of permanent stay of the medical staff.

Surrogacy

• Surrogacy is one of the types of ART (Assisted Reproductive Technologies) in which the process of childbirth is assisted with such parts:

  • the egg and sperm of the biological parents
  • a donated egg fertilized with sperm from the biological father
  • an embryo made with donor egg and sperm

  The child is genetically unrelated to the surrogate mother. The legal conditions and social attitude towards surrogacy in Russia are extremely positive; moreover, the program is able to help couples from the countries where surrogacy is prohibited or it is extremely expensive to become parents. The child is genetically unrelated to the surrogate mother.

  To enter the surrogacy program patients will need following documents:

  • Legalized copies the Russian translations of passports and a marriage certificate.
  • Program eligibility
  • Surrogacy program is offered to officially married couples or single women who have medical contraindications to pregnancy or delivery, or have a record of multiple IVF failure.

  Our surrogate mothers

  Surrogate mothers undergo a thorough medical and psychological screening in accordance with the requirements of the Russian Ministry of Health. This includes: general medical examination, ultrasound scan, infectious disease screening for a variety of infections, drug test, approval by general practitioner, gynecologist, and psychiatrist.

  Surrogate mothers acceptance criteria:

  • age between 20-35 years old 
  • BMI 20-25
  • must have given birth to one or two healthy children
  • uncomplicated pregnancies and deliveries
  • good and somatic health, benevolence, willingness to cooperate
  • non-smoker
  • stable, responsible lifestyle
  • written agreement to undergo the program in compliance with all its conditions

  Program details

  AltraVita IVF clinic can rightly be called "The Surrogate Motherhood Center" since we provide a full range of services: matching the intended parents with the surrogate, her extensive screening, IVF treatment, antenatal care, arranging of childbirth in Moscow maternity hospitals.

  The clinic acts as a Guarantee of the mutual obligations of the intended parents and the surrogate mother. We provide a full social and medical monitoring of surrogate mothers throughout the program. The intended parents will be getting monthly medical reports from the treating physician during the surrogate’s pregnancy. No decision about pregnancy will be made without intended parents’ involvement.

  The intended parents will have to come to Moscow at least 14 days before delivery. After delivery, our lawyer assists with issuing the birth certificate. Our clinic has been practicing surrogacy for the past 16 years and has a good statistics of successful surrogacy for Russian and overseas patients. Altravita IVF clinic will be happy to help you to become parents through this unique method of assisted reproductive technologies.

ICSI/IMSI

• Intracytoplasmic Morphological Sperm Injection (IMSI) is similar to ICSI with the one exception: a doctor before microinjection using a multiple magnification of the microscope - about 6,000 times - carefully examines the sperm, chooses the most "healthy", without pathological changes. Only after that doctor takes a sperm for its introduction into the egg.

NASUM

• This innovative technology allows to study the morphology of sperm at the level of microstructures by zooming in them to a level of 18,000 times.

  The NASUM method is used in cases where a spermogram is not enough to determine a patient's diagnosis. NASUM has no analogues in establishing the form of teratozoospermia, which gives an additional understanding of the causes of impaired fertilization and the normal development of fertilized eggs.

  The unique NASUM method was invented by the AltraVita clinic specialists, which is a clinical branch of the International Medical Center for diagnosis and treatment of male infertility.

IVF with anonymous donor

• Included services

  • Screening, stimulation of ovulation, compensation for anonymous egg donor
  • Scheme of patient’s endometrium preparation for embryo transfer
  • Ovarian puncture with general anesthesia for the egg donor
  • Consultations of reproductive endocrinologist for the patient and the donor
  • Ultrasonic monitor of endometrium for embryo transfer
  • Preparation of sperm for fertilization using two samples of ejaculate
  • ICSI/IMSI
  • Cultivation of embryos until 5-6 day of development
  • Freezing of embryos
  • Fresh embryo transfer to the patient

  Excluded services

  • Additional medication
  • IMSI – if indicated
  • Assisted hatching
  • Embryo biopsy
  • Any type of PGD/PGS
  • Frozen embryo transfer
  • Storage of frozen material
  • Additional consultations of specialists 

IVF tests

• For woman

  • Blood type and Rh factor
  • Complete blood count — valid for 1 month
  • Biochemical blood analysis (Protein total, ALT, AST, Bilirubin total, Urea, Creatinine, Glucose) — valid for 1 year
  • Clinical urine analysis — valid for 1 month
  • Coagulogram (prothrombin, thrombin time, aPTT, fibrinogen concentration) — valid for 1 month
  • Smear for flora from urethra, cervix, vagina — valid for 1 month
  • Blood test for detection of HIV, Syphilis, Hepatitis B and C  (must be done only at AltraVita clinic) — valid for 3 months
  • Hormonal screening (AMH, LH, FSH, Prolactin on day 2-3 of menstrual cycle, T4 free, TSH) — valid for 6 months
  • Smear for cytology from endo and exocervix — valid for 1 year
  • Mammary ultrasound (under 35 y.o) — valid for 1 year
  • Mammography (35 y.o. and over) — valid for 1 year
  • Pelvic ultrasound — valid for 1 year
  • Thyroid ultrasound — valid for 1 year
  • Chest X-Ray — valid for 1 year
  • Physician conclusion — valid for 1 year
  • ECG — valid for 1 year

  Medically indicated tests (upon doctor’s request)

  • СА125 before second IVF program
  • Hysteroscopy, endometrial pipelle biopsy are performed for more detailed examination of endometrial tissue
  • Karyotype blood test is done once in life

  For man

  • Blood type and Rh factor
  • Blood test for detection of HIV, Syphilis, Hepatitis B and C  (must be done only at AltraVita clinic) — valid for 6 months
  • Semen analysis (must be done only at AltraVita clinic) — valid for 3 months

  Medically indicated tests (upon doctor’s request)

  • Karyotype blood test is done once in life
  • Depending on the results of medical tests, patients may be asked to visit the following specialists
  • geneticist
  • breast oncologist
  • endocrinologist
  • psychiatrist
  • infectious disease specialist

IVF

• Whom is IVF treatment suitable?

  • Women who have been diagnosed with unexplained infertility
  • Women with fallopian tubes obstruction
  • When other techniques such as fertility medication or intrauterine insemination (IUI) have not been successful
  • When a limited number of oocytes are available
  • Male partner has serious fertility problems
  • Couples are using donated eggs or their own frozen eggs in their treatment
  • Couples are using preimplantation genetic screening to avoid passing on a genetic condition to the child

  IVF Treatment steps

  • Consultation with reproductive endocrinologist; selection of the individual stimulation protocol.
  • Ovulation induction according to the protocol chosen in order to ensure a higher number of eggs.
  • Monitoring of the hormonal stimulation under ultrasound. The number of matured eggs and quality of uterine lining will be checked.
  • Egg retrieval is performed by gynecologist under general anesthesia. The whole procedure takes 10-20 minutes.
  • Sperm collection, analysis and preparation. Semen is prepared for fertilisation by removing inactive cells and seminal fluid in a process called sperm washing.
  • Fertilisation using ICSI or IMSI methods.
  • Cultivation of embryos. The produced embryos are being cultivated in special incubators for 5-6 days. Their development is closely monitored by experienced embryologists. If necessary, PGS or PGD can be performed to select embryos free from genetic diseases. 
  • Embryo transfer is a painless transfer of the best embryo into the woman’s uterus. Spare embryos will be cryopreserved by vitrification.

  Frozen embryo transfer is one of ART techniques. Many couples choose to try frozen embryo transfer program after a successful IVF attempt to have a second baby.

Noninvasive prenatal testing (NIPT)

• NIPT helps to learn a lot about the baby during the first trimester. This is the most progressive way to diagnose chromosomal disorders and other abnormalities, utilized in all developed countries in the world.

  The testing analyzes small fragments of DNA that are circulating in a pregnant woman’s blood.

  The testing is recommended when:

  • The woman is older than 35 years old;
  • Possible genetic abnormalities suspicions after the ultrasound;
  • The pregnancy achieved with the use of IVF or other VRT 
  • The risk of genetic abnormalities detected during the biochemical screening;
  • Genetic abnormalities detected in other children’s DNA;
  • A history of stillbirth;
  • Premature labor or recurrent miscarriage;
  • Unexplained infertility.

  The key advantages of NIPT include its high accuracy and safety. The possibility of diagnostic mistake is only 0.01%. 

  For this testing, the mother’s venous blood is used. The blood taking procedure is completely safe for both the baby, and the mother.

  One more advantage is that the testing can be performed very early in the pregnancy – in the 9th week. 

  Diagnostic capabilities of the testing

  The testing can detect the following diseases and abnormalities:

  • Down syndrome;
  • Edwards syndrome;
  • Patau syndrome;
  • Turner syndrome;
  • Klinefelter syndrome;
  • Triple X syndrome;
  • Double Y syndrome.

  While analyzing the fetus’ DNA, it is possible to identify its sex.

  Even though NIPT is a high-accuracy method of diagnosis, it is, nevertheless, a screening test. Which means that should any abnormalities be detected during the testing, they still must be confirmed by an invasive test, such as fetal karyotyping. 

  The testing is not performed:

  • Earlier then the 9th week of pregnancy;
  • If selective (multifetal) reduction has been performed;
  • In cases of multifetal pregnancies with three or more fetuses;
  • When the baby is carried by a surrogate mother;
  • When the pregnancy is achieved by means of IVF with the use of donor oocytes.

  If you would like to get more information about this method of diagnosis, please, contact the clinic by phone or via the online inquiry form.

Cryobank