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Natural Cycle IVF

Nowadays IVF in the natural cycle has virtually no contraindications. The main condition for using this method is the presence of a regular ovulatory menstrual cycle.

IVF in natural cycle
123 500 RUR

What is IVF in natural cycle? Ultrasound monitoring of growth of the dominant follicle in the ovary of the patients with preserved ovulation.

With a follicle size of 18 mm, either under the control of an ovulation test, or after the intramuscular injection of an ovulation trigger, a follicle is punctured to obtain an egg. The rest of the IVF program process remains the same.

To increase the effectiveness of IVF, the program includes the study of egg’s spindle apparatus. This procedure is carried out on a special apparatus called Poloscope, which allows to examine the spindle, identify defects that can subsequently lead to the development of chromosomal abnormalities. The usage of this technique can increase the chances of implantation and pregnancy and minimize the risk of miscarriage and the birth of a sick child. The rest of the IVF program process remains the same.

The package includes (depending on the Doctor’s prescription)

  • Prescribing natural cycle treatment plan;
  • Consultation with Infertility doctor (up to 3 times);
  • Follicle ultrasound (up to 3 times);
  • Hormone level tests for monitoring ovarian stimulation (LH, estradiol, progesterone express-tests – up to 3 times)
  • One of the following medications:
  • Diphereline (0.1)
  • Chorionic gonadotropin (up to 10.000)
  • Ovarian puncture in natural cycle
  • Staying in a hospital ward for 3 hours for monitoring purposes
  • Embryological stage:
  • Oocyte identification and assessment; 
  • 2 sperm specimen preparation for fertilization;
  • In vitro fertilization: ICSI;
  • Embryo culture;
  • Oocyte spindle apparatus assessment.

The package does not include

  • Medications that are not listed in the program description;
  • Medical assistance in case of emergency conditions;
  • IMSI;
  • Assisted hatching;
  • Embryo biopsy;
  • All kinds of preimplantation genetic diagnosis;
  • Embryo storage;
  • All consultations with related specialists;
  • The use of donor material and its defrosting.

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Usually one ovule ripens in the ovaries, which is then extracted by the puncture method, after which the turn of its fertilization begins.

In order to simultaneously obtain several mature eggs during IVF, hormonal stimulation is often used. This process usually is positively perceived by the female body. However, it is worth considering that hormonal stimulation is still a rather serious test for a woman, subjecting her body to increased stress. This is the main reason why women are interested in how much IVF costs in the natural cycle. They want to minimize the risk of side effects of drugs.

For some patients, the introduction of significant doses of hormonal drugs is unacceptable due to intolerance to their body. Some patients want to avoid hormonal effects on the body or have contraindications for the induction of superovulation. Therefore, an alternative method of obtaining an egg for these women can be carried out by IVF in the natural menstrual cycle.

IVF in the natural cycle: pros and cons

The reason for the low demand for IVF in the natural menstrual cycle is that it is characterized by a fairly low efficiency. In most cases, reproductologists prescribe ovulation stimulation rather than IVF in the natural cycle. Statistics do not speak in favor of this method of fertilization. The pregnancy rate is lower than with insemination in the natural cycle, it is about 7% in terms of each started cycle.

This is due to the fact that not every mature follicle is an egg carrier. In addition, because of the puncture, only one egg is extracted, which may not be able to fertilize. Also, when using this method, there is a risk of canceling the oocyte collection procedure due to premature ovulation. But reviews of IVF in the natural cycle attest to its significant advantages.

The advantage of this method is to minimize the risk of complications such as ovarian hyperstimulation syndrome.

The undoubted advantages of the IVF method in the natural cycle include the possibility of carrying out the procedure for several menstrual cycles in a row. However, do not forget, that a single puncture of stimulated ovaries will do less harm than multiple.

Special preparation for IVF in the natural cycle is not required. You do not need to take hormonal drugs. Most women are negative about drug stimulation, and for this reason they prefer IVF in the natural cycle. A forum or social networks where you can read reviews and comments is an eloquent testimony to this.

Another plus of IVF in the natural cycle is the price. It is lower than with IVF with stimulation, in addition, you do not need to spend money on hormonal drugs.

IVF in the natural cycle - cost

Compared with other programs of reproductive technologies, the cost of IVF in the natural cycle is lower than in programs where superovulation was induced with hormonal drugs. But it can vary depending on the patient’s age, ovarian condition, and lifestyle. However, the treatment process is purely individual, so it is better to get information about the cost from the doctor.

IVM procedure

IVM means in vitro egg maturation (in vitro) followed by IVF. The specialists of AltraVita clinic have sufficient capabilities and knowledge to conduct this process with high efficiency, as evidenced by reviews of IVF in natural cycle.

IVM involves the extraction of ovum from an ovary in an immature state, after which it is placed in special media, which are ideal for the final maturation of the egg. This is achieved by creating the optimal hormonal balance in them. The advantage of the IVM method is that the female body is practically not exposed to hormonal stress, and sometimes it is completely absent. After the eggs are ripened in vitro, fertilization is carried out using the IMSI method, embryos are cultured, their quality is assessed and transferred to the uterus.

The combination of IVM and IVF methods in natural hormonal cycle

The combination of IVM and IVF methods makes it possible to simultaneously obtain a mature egg from a dominant follicle and a number of immature eggs from small (antral) follicles. Egg maturation takes place “in vitro”, and a mature egg undergoes fertilization in the standard way. High-quality embryos obtained by both methods are transferred into the uterus.

Indications for IVF in the natural cycle in conjunction with IVM

  • Polycystic Ovary Syndrome
  • Significant risk of ovarian hyperstimulation syndrome
  • A history of benign hormone-dependent tumors
  • Contraindications to the induction of superovulation

Factors Affecting IVM Choice

  • The ability to avoid the risk of developing ovarian hyperstimulation syndrome

  • Lack of hormonal stimulation
  • Affordable cost of the procedure, which is caused by a small amount of hormonal drugs used


Thank you so much, Dr. Vladimir Valentinovich, you are both a wonderful person and an exceptional specialist!!! Thanks to your treatment and unique approach, on April 10 we had our precious little girl. You always knew exactly what to say to cheer us up. Despite all the failures, you never lost hope and kept coming up with new treatment plans until at the long last we finally succeeded.  I thank…
2019-10-15 Read more
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I am ever so grateful to Dr. Asharina, who managed to give me hope on one day becoming a mother again. After a miscarriage with severe complications, all other doctors would only shrug and tell me to try harder and keep waiting.  Dr. Asharina, on the other hand, figured out the problem during the very first visit and prescribed the suitable treatment. Now, we are hoping for positive results.    
2019-10-03 Read more
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I’d like to thank the Altravita management for employing such an amazing doctor like Saida A. Magomedova. She is indeed an outstanding specialist in her field. Dr. Magomedova is calm, patient, polite and, more importantly, very experienced! Even though she doesn’t have that many years of experience, she is highly knowledgeable in the area. Thanks to her skills, me and my husband became parents! Thank…
2019-09-17 Read more
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Dr. Zarema Beckkhanovna, there’s so many thoughts in my head, but it’s still not enough to express how grateful we are to you. Thank you for our Son, please, except our deepest and most sincere gratitude.  Thank you for your smiles, encouraging words, warm hugs before the transfer. Thank you for when the test results came in you told us: “We are going”. And so we went. We have come a long way through…
2019-09-12 Read more
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I first went to see Elena Alexandrovna in June. My spermogram was bad. The doctor said that was because of my hormones level and prescribed a treatment plan. After a month, we could already see positive changes. Although it’s still not perfect, I’m hoping for further improvements. The medicine is expensive, but it really works. It’s obvious that the Doctor know what she is doing. They do tests and…
2019-09-11 Read more
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